Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Viruses suppress host responses to increase infection, and understanding these mechanisms has provided insights into cellular signaling and led to novel therapies. Many viruses (e.g., Influenza virus, Rhinovirus [RV], Cytomegalovirus, Epstein-Barr virus, and Hepatitis C virus) activate epithelial ep...

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Detalles Bibliográficos
Autores principales: Ueki, Iris F., Min-Oo, Gundula, Kalinowski, April, Ballon-Landa, Eric, Lanier, Lewis L., Nadel, Jay A., Koff, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782052/
https://www.ncbi.nlm.nih.gov/pubmed/23999497
http://dx.doi.org/10.1084/jem.20121401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782052/
https://www.ncbi.nlm.nih.gov/pubmed/23999497
http://dx.doi.org/10.1084/jem.20121401

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