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Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism

Dendritic cells (DCs) in the intestinal lamina propria (LP) are composed of two CD103(+) subsets that differ in CD11b expression. We report here that Langerin is expressed by human LP DCs and that transgenic human langerin drives expression in CD103(+)CD11b(+) LP DCs in mice. This subset was ablated...

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Detalles Bibliográficos
Autores principales: Welty, Nathan E., Staley, Christopher, Ghilardi, Nico, Sadowsky, Michael J., Igyártó, Botond Z., Kaplan, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782055/
https://www.ncbi.nlm.nih.gov/pubmed/24019552
http://dx.doi.org/10.1084/jem.20130728