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B7x and myeloid-derived suppressor cells in the tumor microenvironment: A tale of two cities
A new study demonstrates the tumorigenic functions of B7x and reveals a link between B7x and myeloid-derived suppressor cells (MDSCs) within the tumor microenvironment. We propose that the binding of B7x to a hitherto unidentified receptor on MDSCs may stimulate their proliferation and/or immunosupp...
Autores principales: | Jeon, Hyungjun, Ohaegbulam, Kim C, Abadi, Yael M, Zang, Xingxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782163/ https://www.ncbi.nlm.nih.gov/pubmed/24073367 http://dx.doi.org/10.4161/onci.24744 |
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