High immunosuppressive burden in advanced hepatocellular carcinoma patients: Can effector functions be restored?

The accumulation of immunosuppressive cells and exhausted effector T cells highlight an important immune dysfunction in advanced stage hepatocellular carcinoma (HCC) patients. These cells significantly hamper the efficacy immunotherapies and facilitate HCC progression. We have recently demonstrated...

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Detalles Bibliográficos
Autores principales: Lugade, Amit A, Kalathil, Suresh, Miller, Austin, Iyer, Renuka, Thanavala, Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782165/
https://www.ncbi.nlm.nih.gov/pubmed/24073364
http://dx.doi.org/10.4161/onci.24679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782165/
https://www.ncbi.nlm.nih.gov/pubmed/24073364
http://dx.doi.org/10.4161/onci.24679

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