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HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium

BACKGROUND: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation. Therefore, we hypothesized that mechanical ventilation and concomitant stretch-exposure of p...

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Detalles Bibliográficos
Autores principales: Eckle, Tobias, Brodsky, Kelley, Bonney, Megan, Packard, Thomas, Han, Jun, Borchers, Christoph H., Mariani, Thomas J., Kominsky, Douglas J., Mittelbronn, Michel, Eltzschig, Holger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782424/
https://www.ncbi.nlm.nih.gov/pubmed/24086109
http://dx.doi.org/10.1371/journal.pbio.1001665