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HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium
BACKGROUND: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation. Therefore, we hypothesized that mechanical ventilation and concomitant stretch-exposure of p...
Autores principales: | Eckle, Tobias, Brodsky, Kelley, Bonney, Megan, Packard, Thomas, Han, Jun, Borchers, Christoph H., Mariani, Thomas J., Kominsky, Douglas J., Mittelbronn, Michel, Eltzschig, Holger K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782424/ https://www.ncbi.nlm.nih.gov/pubmed/24086109 http://dx.doi.org/10.1371/journal.pbio.1001665 |
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