PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage

Amyloid beta peptide (Aβ) causes neurodegeneration by several mechanisms including oxidative stress, which is known to induce DNA damage with the consequent activation of poly (ADP-ribose) polymerase (PARP-1). To elucidate the role of PARP-1 in the neurodegenerative process, SH-SY5Y neuroblastoma ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Martire, Sara, Fuso, Andrea, Rotili, Dante, Tempera, Italo, Giordano, Cesare, De Zottis, Ivana, Muzi, Alessia, Vernole, Patrizia, Graziani, Grazia, Lococo, Emanuela, Faraldi, Martina, Maras, Bruno, Scarpa, Sigfrido, Mosca, Luciana, d'Erme, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782458/
https://www.ncbi.nlm.nih.gov/pubmed/24086258
http://dx.doi.org/10.1371/journal.pone.0072169

Ejemplares similares

Ejemplares similares