Usage of Adenovirus Expressing Thymidine Kinase Mediated Hepatocellular Damage for Enabling Mouse Liver Repopulation with Allogenic or Xenogenic Hepatocytes

It has been shown that the liver of immunodeficient mice can be efficiently repopulated with human hepatocytes when subjected to chronic hepatocellular damage. Mice with such chimeric livers represent useful reagents for medical and clinical studies. However all previously reported models of humaniz...

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Detalles Bibliográficos
Autores principales: Moreno, Daniel, Balasiddaiah, Anangi, Lamas, Oscar, Duret, Cedric, Neri, Leire, Guembe, Laura, Galarraga, Miguel, Larrea, Esther, Daujat-Chavanieu, Martine, Muntane, Jordi, Maurel, Patrick, Riezu, Jose Ignacio, Prieto, Jesus, Aldabe, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782477/
https://www.ncbi.nlm.nih.gov/pubmed/24086405
http://dx.doi.org/10.1371/journal.pone.0074948

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