Toll-Like Receptor 2 or Toll-Like Receptor 4 Deficiency Does Not Modify Lupus in MRLlpr Mice

Systemic lupus erythematosus is an autoimmune disease with a high morbidity and nephritis is a common manifestation. Previous studies in murine lupus models have suggest a role for Toll-like receptor 2 and 4. We examined the role of these molecules in MRL lpr mice which is one of the most establishe...

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Detalles Bibliográficos
Autores principales: Freeley, Simon J., Giorgini, Angela, Tulone, Calogero, Popat, Reena J., Horsfield, Catherine, Robson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782491/
https://www.ncbi.nlm.nih.gov/pubmed/24086313
http://dx.doi.org/10.1371/journal.pone.0074112

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