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Myeloid-derived suppressor cells as a Trojan horse: A cellular vehicle for the delivery of oncolytic viruses

We have recently demonstrated that oncolytic vesicular stomatitis viruses can be efficiently and selectively delivered to neoplastic lesions by myeloid-derived suppressor cells (MDSCs). Importantly, the loading of viruses onto MDSCs inhibited their immunosuppressive properties and endowed them with...

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Detalles Bibliográficos
Autores principales: Pan, Ping-Ying, Chen, Hui-ming, Chen, Shu-Hsia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782526/
https://www.ncbi.nlm.nih.gov/pubmed/24083075
http://dx.doi.org/10.4161/onci.25083

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