TNF inhibitors induce discoid fibrosis in the sublining layers of the synovium with degeneration of synoviocytes in rheumatoid arthritis

We determined the characteristic features of synovial tissues of rheumatoid arthritis (RA) patients treated by TNF inhibitors in order to delineate their mechanism of action. Synovial tissues were obtained during the joint surgical operations from 12 RA patients who had been treated with TNF inhibit...

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Detalles Bibliográficos
Autores principales: Hirohata, Shunsei, Tomita, Tetsuya, Yoshikawa, Hideki, Kyogoku, Masahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782653/
https://www.ncbi.nlm.nih.gov/pubmed/23575549
http://dx.doi.org/10.1007/s00296-013-2743-y

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