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PedWiz: a web-based tool for pedigree informatics
A novel web-based tool PedWiz that pipelines the informatics process for pedigree data is introduced. PedWiz is designed to assist researchers in the analysis of pedigree data. It provides a convenient tool for pedigree informatics: descriptive statistics, relative pairs, genetic similarity coeffici...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782697/ https://www.ncbi.nlm.nih.gov/pubmed/24093024 http://dx.doi.org/10.3389/fgene.2013.00189 |
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author | Song, Yeunjoo E. Elston, Robert C. |
author_facet | Song, Yeunjoo E. Elston, Robert C. |
author_sort | Song, Yeunjoo E. |
collection | PubMed |
description | A novel web-based tool PedWiz that pipelines the informatics process for pedigree data is introduced. PedWiz is designed to assist researchers in the analysis of pedigree data. It provides a convenient tool for pedigree informatics: descriptive statistics, relative pairs, genetic similarity coefficients, the variance-covariance matrix for three estimated coefficients of allele identical-by-descent sharing as well as mean allele sharing, a plot of the pedigree structures, and a visualization of the identity coefficients. With a renewed interest in linkage and other family based methods, PedWiz will be a valuable tool for the analysis of family data. |
format | Online Article Text |
id | pubmed-3782697 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-37826972013-10-03 PedWiz: a web-based tool for pedigree informatics Song, Yeunjoo E. Elston, Robert C. Front Genet Genetics A novel web-based tool PedWiz that pipelines the informatics process for pedigree data is introduced. PedWiz is designed to assist researchers in the analysis of pedigree data. It provides a convenient tool for pedigree informatics: descriptive statistics, relative pairs, genetic similarity coefficients, the variance-covariance matrix for three estimated coefficients of allele identical-by-descent sharing as well as mean allele sharing, a plot of the pedigree structures, and a visualization of the identity coefficients. With a renewed interest in linkage and other family based methods, PedWiz will be a valuable tool for the analysis of family data. Frontiers Media S.A. 2013-09-25 /pmc/articles/PMC3782697/ /pubmed/24093024 http://dx.doi.org/10.3389/fgene.2013.00189 Text en Copyright © Song and Elston. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Song, Yeunjoo E. Elston, Robert C. PedWiz: a web-based tool for pedigree informatics |
title | PedWiz: a web-based tool for pedigree informatics |
title_full | PedWiz: a web-based tool for pedigree informatics |
title_fullStr | PedWiz: a web-based tool for pedigree informatics |
title_full_unstemmed | PedWiz: a web-based tool for pedigree informatics |
title_short | PedWiz: a web-based tool for pedigree informatics |
title_sort | pedwiz: a web-based tool for pedigree informatics |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782697/ https://www.ncbi.nlm.nih.gov/pubmed/24093024 http://dx.doi.org/10.3389/fgene.2013.00189 |
work_keys_str_mv | AT songyeunjooe pedwizawebbasedtoolforpedigreeinformatics AT elstonrobertc pedwizawebbasedtoolforpedigreeinformatics |