Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

BACKGROUND: While aerobic glycolysis is linked to unconstrained proliferation in cancer, less is known about its physiological role. Why this metabolic program that promotes tumor growth is preserved in the genome has thus been unresolved. We tested the hypothesis that aerobic glycolysis derives fro...

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Detalles Bibliográficos
Autores principales: Gershon, Timothy R, Crowther, Andrew J, Tikunov, Andrey, Garcia, Idoia, Annis, Ryan, Yuan, Hong, Miller, C Ryan, Macdonald, Jeffrey, Olson, James, Deshmukh, Mohanish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782751/
https://www.ncbi.nlm.nih.gov/pubmed/24280485
http://dx.doi.org/10.1186/2049-3002-1-2

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