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Attachment site recognition and regulation of directionality by the serine integrases

Serine integrases catalyze the integration of bacteriophage DNA into a host genome by site-specific recombination between ‘attachment sites’ in the phage (attP) and the host (attB). The reaction is highly directional; the reverse excision reaction between the product attL and attR sites does not occ...

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Detalles Bibliográficos
Autores principales: Rutherford, Karen, Yuan, Peng, Perry, Kay, Sharp, Robert, Van Duyne, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783163/
https://www.ncbi.nlm.nih.gov/pubmed/23821671
http://dx.doi.org/10.1093/nar/gkt580