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Mineralocorticoid receptor interaction with SP1 generates a new response element for pathophysiologically relevant gene expression

The mineralocorticoid receptor (MR) is a ligand-induced transcription factor belonging to the steroid receptor family and involved in water-electrolyte homeostasis, blood pressure regulation, inflammation and fibrosis in the renocardiovascular system. The MR shares a common hormone-response-element...

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Detalles Bibliográficos
Autores principales: Meinel, Sandra, Ruhs, Stefanie, Schumann, Katja, Strätz, Nicole, Trenkmann, Kay, Schreier, Barbara, Grosse, Ivo, Keilwagen, Jens, Gekle, Michael, Grossmann, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783164/
https://www.ncbi.nlm.nih.gov/pubmed/23821666
http://dx.doi.org/10.1093/nar/gkt581