The Non-Protein Amino Acid BMAA Is Misincorporated into Human Proteins in Place of l-Serine Causing Protein Misfolding and Aggregation

Mechanisms of protein misfolding are of increasing interest in the aetiology of neurodegenerative diseases characterized by protein aggregation and tangles including Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy Body Dementia (LBD), and Progressive Sup...

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Detalles Bibliográficos
Autores principales: Dunlop, Rachael Anne, Cox, Paul Alan, Banack, Sandra Anne, Rodgers, Kenneth John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783393/
https://www.ncbi.nlm.nih.gov/pubmed/24086518
http://dx.doi.org/10.1371/journal.pone.0075376

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