Cargando…
Overexpression of Meloe Gene in Melanomas Is Controlled Both by Specific Transcription Factors and Hypomethylation
The melanoma antigens MELOE-1 and MELOE-2 are encoded by a messenger, called meloe, overexpressed in melanomas compared with other tumour cell types and healthy tissues. They are both able to elicit melanoma-specific T cell responses in melanoma patients, and MELOE-1-specific CD8 T cells have been i...
Autores principales: | Bobinet, Mathilde, Vignard, Virginie, Florenceau, Laetitia, Lang, Francois, Labarriere, Nathalie, Moreau-Aubry, Agnès |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783405/ https://www.ncbi.nlm.nih.gov/pubmed/24086527 http://dx.doi.org/10.1371/journal.pone.0075421 |
Ejemplares similares
-
The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences
por: Carbonnelle, Delphine, et al.
Publicado: (2013) -
MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients
por: Bobinet, Mathilde, et al.
Publicado: (2012) -
MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency
por: Godet, Yann, et al.
Publicado: (2008) -
IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens
por: Charpentier, Maud, et al.
Publicado: (2016) -
PD-1 expression conditions T cell avidity within an antigen-specific repertoire
por: Simon, Sylvain, et al.
Publicado: (2015)