Antagonism of Betulinic Acid on LPS-Mediated Inhibition of ABCA1 and Cholesterol Efflux through Inhibiting Nuclear Factor-kappaB Signaling Pathway and miR-33 Expression

ATP-binding cassette transporter A1 (ABCA1) is critical in exporting cholesterol from macrophages and plays a protective role in the development of atherosclerosis. The purpose of this study was to investigate the effects of betulinic acid (BA), a pentacyclic triterpenoid, on ABCA1 expression and ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Guo-Jun, Tang, Shi-Lin, Lv, Yun-Cheng, Ouyang, Xin-Ping, He, Ping-Ping, Yao, Feng, Chen, Wu-Jun, Lu, Qian, Tang, Yan-Yan, Zhang, Min, Fu, Yuchang, Zhang, Da-Wei, Yin, Kai, Tang, Chao-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783495/
https://www.ncbi.nlm.nih.gov/pubmed/24086374
http://dx.doi.org/10.1371/journal.pone.0074782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783495/
https://www.ncbi.nlm.nih.gov/pubmed/24086374
http://dx.doi.org/10.1371/journal.pone.0074782

Ejemplares similares