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Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience

INTRODUCTION: Fournier's gangrene is an aggressive disease with high morbidity and mortality. The aim of this study was to assess risk factors associated with mortality among patients of Fournier's gangrene. MATERIALS AND METHODS: Between May 2011 and September 2012, all patients of Fourni...

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Autores principales: Vyas, Hari Gopal, Kumar, Anup, Bhandari, Vimal, Kumar, Niraj, Jain, Abhinav, Kumar, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783691/
https://www.ncbi.nlm.nih.gov/pubmed/24082432
http://dx.doi.org/10.4103/0970-1591.117255
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author Vyas, Hari Gopal
Kumar, Anup
Bhandari, Vimal
Kumar, Niraj
Jain, Abhinav
Kumar, Rohit
author_facet Vyas, Hari Gopal
Kumar, Anup
Bhandari, Vimal
Kumar, Niraj
Jain, Abhinav
Kumar, Rohit
author_sort Vyas, Hari Gopal
collection PubMed
description INTRODUCTION: Fournier's gangrene is an aggressive disease with high morbidity and mortality. The aim of this study was to assess risk factors associated with mortality among patients of Fournier's gangrene. MATERIALS AND METHODS: Between May 2011 and September 2012, all patients of Fournier's gangrene treated at our center were included in the study. All patients underwent emergency surgical debridement and received broad spectrum intravenous antibiotics. Their baseline characteristics, treatment, and follow-up data were recorded and analyzed. RESULTS: A total of 30 patients were included in the study. Of these, six patients (20%) died during the treatment. Age <55 years, total leukocyte count <15000 cumm, extent of the area involved, septic shock at admission, visual analog scale (VAS) <7 at admission, and Fournier gangrene severity index (FGSI) score <8 at admission were significantly associated with increased mortality. CONCLUSION: In patients of Fournier's gangrene, increased age, total leukocyte count, extent of the area involved, septic shock at admission, VAS score, and FGSI score at admission have a significant association with mortality.
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spelling pubmed-37836912013-09-30 Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience Vyas, Hari Gopal Kumar, Anup Bhandari, Vimal Kumar, Niraj Jain, Abhinav Kumar, Rohit Indian J Urol Original Article INTRODUCTION: Fournier's gangrene is an aggressive disease with high morbidity and mortality. The aim of this study was to assess risk factors associated with mortality among patients of Fournier's gangrene. MATERIALS AND METHODS: Between May 2011 and September 2012, all patients of Fournier's gangrene treated at our center were included in the study. All patients underwent emergency surgical debridement and received broad spectrum intravenous antibiotics. Their baseline characteristics, treatment, and follow-up data were recorded and analyzed. RESULTS: A total of 30 patients were included in the study. Of these, six patients (20%) died during the treatment. Age <55 years, total leukocyte count <15000 cumm, extent of the area involved, septic shock at admission, visual analog scale (VAS) <7 at admission, and Fournier gangrene severity index (FGSI) score <8 at admission were significantly associated with increased mortality. CONCLUSION: In patients of Fournier's gangrene, increased age, total leukocyte count, extent of the area involved, septic shock at admission, VAS score, and FGSI score at admission have a significant association with mortality. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3783691/ /pubmed/24082432 http://dx.doi.org/10.4103/0970-1591.117255 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Vyas, Hari Gopal
Kumar, Anup
Bhandari, Vimal
Kumar, Niraj
Jain, Abhinav
Kumar, Rohit
Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title_full Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title_fullStr Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title_full_unstemmed Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title_short Prospective evaluation of risk factors for mortality in patients of Fournier's gangrene: A single center experience
title_sort prospective evaluation of risk factors for mortality in patients of fournier's gangrene: a single center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783691/
https://www.ncbi.nlm.nih.gov/pubmed/24082432
http://dx.doi.org/10.4103/0970-1591.117255
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