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A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice
Mycobacterium tuberculosis 6-kDa early secretory antigenic target (ESAT-6) is a dominant target antigen for cell-mediated immunity in the early phase of tuberculosis. The fms-like tyrosine kinase 3 ligand (FL) that induces potent immune response has been used as an adjuvant in vaccine development. I...
Autores principales: | Jiang, Qingtao, Zhang, Jing, Chen, Xia, Xia, Mei, Lu, Yanlai, Qiu, Wen, Feng, Ganzhu, Zhao, Dan, Li, Yan, He, Fengxia, Peng, Guangyong, Wang, Yingwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783826/ https://www.ncbi.nlm.nih.gov/pubmed/24086174 http://dx.doi.org/10.7555/JBR.27.20120114 |
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