Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge

The known chromodorolides A (1) and B (2), and a new derivative chromodorolide C (3) have been isolated from an Australian sponge and characterized by 1D and 2D NMR experiments. The chromodorolides exhibited significant cytotoxicity against the P388 mouse leukaemia cell line, and also showed activit...

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Detalles Bibliográficos
Autores principales: Rungprom, Wimolpun, Chavasiri, Warinthorn, Kokpol, Udom, Kotze, Andrew, Garson, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783864/
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author Rungprom, Wimolpun
Chavasiri, Warinthorn
Kokpol, Udom
Kotze, Andrew
Garson, Mary J.
author_facet Rungprom, Wimolpun
Chavasiri, Warinthorn
Kokpol, Udom
Kotze, Andrew
Garson, Mary J.
author_sort Rungprom, Wimolpun
collection PubMed
description The known chromodorolides A (1) and B (2), and a new derivative chromodorolide C (3) have been isolated from an Australian sponge and characterized by 1D and 2D NMR experiments. The chromodorolides exhibited significant cytotoxicity against the P388 mouse leukaemia cell line, and also showed activity against the free-living larval stages of the parasitic nematodes Haemonchus contortus and Trichostrongylus colubriformis.
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spelling pubmed-37838642013-10-17 Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge Rungprom, Wimolpun Chavasiri, Warinthorn Kokpol, Udom Kotze, Andrew Garson, Mary J. Mar Drugs Article The known chromodorolides A (1) and B (2), and a new derivative chromodorolide C (3) have been isolated from an Australian sponge and characterized by 1D and 2D NMR experiments. The chromodorolides exhibited significant cytotoxicity against the P388 mouse leukaemia cell line, and also showed activity against the free-living larval stages of the parasitic nematodes Haemonchus contortus and Trichostrongylus colubriformis. Molecular Diversity Preservation International (MDPI) 2004-08-25 /pmc/articles/PMC3783864/ Text en © 2004 by MDPI Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Rungprom, Wimolpun
Chavasiri, Warinthorn
Kokpol, Udom
Kotze, Andrew
Garson, Mary J.
Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title_full Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title_fullStr Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title_full_unstemmed Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title_short Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge
title_sort bioactive chromodorolide diterpenes from an aplysillid sponge
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783864/
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AT chavasiriwarinthorn bioactivechromodorolidediterpenesfromanaplysillidsponge
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AT kotzeandrew bioactivechromodorolidediterpenesfromanaplysillidsponge
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