Reassembled Biosynthetic Pathway for a Large-scale Synthesis of CMP-Neu5Ac

CMP-Neu5Ac is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates. In this paper, a large-scale production system of CMP-Neu5Ac by a single strain is reported. The co-expression of Neu5Ac aldolase (EC4.1.3.3) and CMP-Neu5Ac synthetase (EC 2.7.7.43) was achieved by constr...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jing, Zhang, Hesheng, Wu, Bingyuan, Zhang, Yingxin, Li, Hanfen, Xiao, Min, Wang, Peng George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783873/

Ejemplares similares

Ejemplares similares