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The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila

The olfactory response of the vinegar fly Drosophila melanogaster to food odor is modulated by starvation. Here we show that this modulation is not restricted to food odors and their detecting sensory neurons but rather increases the behavioral response to odors as different as food odors, repellent...

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Detalles Bibliográficos
Autores principales: Farhan, Abu, Gulati, Jyotasana, Groβe-Wilde, Ewald, Vogel, Heiko, Hansson, Bill S., Knaden, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783891/
https://www.ncbi.nlm.nih.gov/pubmed/24067446
http://dx.doi.org/10.1038/srep02765
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author Farhan, Abu
Gulati, Jyotasana
Groβe-Wilde, Ewald
Vogel, Heiko
Hansson, Bill S.
Knaden, Markus
author_facet Farhan, Abu
Gulati, Jyotasana
Groβe-Wilde, Ewald
Vogel, Heiko
Hansson, Bill S.
Knaden, Markus
author_sort Farhan, Abu
collection PubMed
description The olfactory response of the vinegar fly Drosophila melanogaster to food odor is modulated by starvation. Here we show that this modulation is not restricted to food odors and their detecting sensory neurons but rather increases the behavioral response to odors as different as food odors, repellents and pheromones. The increased behavioral responsiveness is paralleled by an increased physiological sensitivity of sensory neurons regardless whether they express olfactory or ionotropic receptors and regardless whether they are housed in basiconic, coeloconic, or trichoid sensilla. Silencing several genes that become up-regulated under starvation confirmed the involvement of the short neuropeptide f receptor in the starvation effect. In addition it revealed that the CCHamide-1 receptor is another important factor governing starvation-induced olfactory modifications.
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spelling pubmed-37838912013-09-30 The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila Farhan, Abu Gulati, Jyotasana Groβe-Wilde, Ewald Vogel, Heiko Hansson, Bill S. Knaden, Markus Sci Rep Article The olfactory response of the vinegar fly Drosophila melanogaster to food odor is modulated by starvation. Here we show that this modulation is not restricted to food odors and their detecting sensory neurons but rather increases the behavioral response to odors as different as food odors, repellents and pheromones. The increased behavioral responsiveness is paralleled by an increased physiological sensitivity of sensory neurons regardless whether they express olfactory or ionotropic receptors and regardless whether they are housed in basiconic, coeloconic, or trichoid sensilla. Silencing several genes that become up-regulated under starvation confirmed the involvement of the short neuropeptide f receptor in the starvation effect. In addition it revealed that the CCHamide-1 receptor is another important factor governing starvation-induced olfactory modifications. Nature Publishing Group 2013-09-26 /pmc/articles/PMC3783891/ /pubmed/24067446 http://dx.doi.org/10.1038/srep02765 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Article
Farhan, Abu
Gulati, Jyotasana
Groβe-Wilde, Ewald
Vogel, Heiko
Hansson, Bill S.
Knaden, Markus
The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title_full The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title_fullStr The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title_full_unstemmed The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title_short The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila
title_sort cchamide 1 receptor modulates sensory perception and olfactory behavior in starved drosophila
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783891/
https://www.ncbi.nlm.nih.gov/pubmed/24067446
http://dx.doi.org/10.1038/srep02765
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