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Sporadic Occurrence of Jarcho-Levin Syndrome in an Ivorian Newborn

We report on an isolated chest-wall asymmetry with imaging findings of multiple vertebral and related rib defects in an Ivorian male newborn. He was born of a healthy and young couple without parental lineage, neither family malformative history nor teratogen exposure. This clinical presentation adv...

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Detalles Bibliográficos
Autores principales: Odéhouri-Koudou, Thierry Hervé, Yaokreh, Jean-baptiste, Tembély, Samba, Dick, Rufin Kobinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784160/
https://www.ncbi.nlm.nih.gov/pubmed/24106627
http://dx.doi.org/10.1155/2013/129625
Descripción
Sumario:We report on an isolated chest-wall asymmetry with imaging findings of multiple vertebral and related rib defects in an Ivorian male newborn. He was born of a healthy and young couple without parental lineage, neither family malformative history nor teratogen exposure. This clinical presentation advocates Jarcho-Levin syndrome, a rare sporadic or familial disorder inherited as autosomal dominant or recessive mode and manifested by extensive vertebral segmentation defects with distinctive rib structural and morphological anomalies. According to our belief, this disorder has not been previously traced in the sub-Saharan African area.