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Lost therapeutic potential of monocyte-derived dendritic cells through lost tissue homing: stable restoration of gut specificity with retinoic acid

Human monocyte-derived dendritic cells (DC) (MoDC) are utilized for immunotherapy. However, in-vitro immunological effects are often not mirrored in vivo. We studied the tissue-homing potential of MoDC. Circulating monocytes and DC expressed different tissue-homing markers and, during in-vitro devel...

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Detalles Bibliográficos
Autores principales: Bernardo, D, Mann, E R, Al-Hassi, H O, English, N R, Man, R, Lee, G H, Ronde, E, Landy, J, Peake, S T C, Hart, A L, Knight, S C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784218/
https://www.ncbi.nlm.nih.gov/pubmed/23607934
http://dx.doi.org/10.1111/cei.12118