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Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass

Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% o...

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Autores principales: Moloney, Fiachra, Twomey, Maria, Hinchion, John, Maher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784231/
https://www.ncbi.nlm.nih.gov/pubmed/24106632
http://dx.doi.org/10.1155/2013/130515
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author Moloney, Fiachra
Twomey, Maria
Hinchion, John
Maher, Michael
author_facet Moloney, Fiachra
Twomey, Maria
Hinchion, John
Maher, Michael
author_sort Moloney, Fiachra
collection PubMed
description Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% of cases. We present a case of a pleural mass located posteriorly in a paraspinal location, which was discovered incidentally in a 50-year-old man and was subsequently resected followed by an unexpected diagnosis of Castleman disease on histological examination. In this report, we review the clinical and histological findings in a rare presentation of Castleman disease and discuss the findings in this case as part of an overall review of the typical radiological findings seen in Castleman disease.
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spelling pubmed-37842312013-10-08 Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass Moloney, Fiachra Twomey, Maria Hinchion, John Maher, Michael Case Rep Radiol Case Report Castleman disease (CD) is a rare benign lymphoproliferative disorder, the etiology of which is unclear. Clinically it may manifest as localized disease (unicentric) or disseminated disease (multicentric). CD occurs in the thorax in 70% of cases, abdomen and pelvis in 15%, and in the neck in 10–15% of cases. We present a case of a pleural mass located posteriorly in a paraspinal location, which was discovered incidentally in a 50-year-old man and was subsequently resected followed by an unexpected diagnosis of Castleman disease on histological examination. In this report, we review the clinical and histological findings in a rare presentation of Castleman disease and discuss the findings in this case as part of an overall review of the typical radiological findings seen in Castleman disease. Hindawi Publishing Corporation 2013 2013-09-11 /pmc/articles/PMC3784231/ /pubmed/24106632 http://dx.doi.org/10.1155/2013/130515 Text en Copyright © 2013 Fiachra Moloney et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Moloney, Fiachra
Twomey, Maria
Hinchion, John
Maher, Michael
Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_full Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_fullStr Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_full_unstemmed Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_short Castleman Disease: An Unexpected Cause of a Solitary Pleural Mass
title_sort castleman disease: an unexpected cause of a solitary pleural mass
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784231/
https://www.ncbi.nlm.nih.gov/pubmed/24106632
http://dx.doi.org/10.1155/2013/130515
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