Long-term dynamics of CA1 hippocampal place codes

Via Ca(2+)-imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, for each day the ensemble representation of this environment involved a unique subset of cells. Yet, cells...

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Detalles Bibliográficos
Autores principales: Ziv, Yaniv, Burns, Laurie D., Cocker, Eric D., Hamel, Elizabeth O., Ghosh, Kunal K., Kitch, Lacey J., El Gamal, Abbas, Schnitzer, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784308/
https://www.ncbi.nlm.nih.gov/pubmed/23396101
http://dx.doi.org/10.1038/nn.3329
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author Ziv, Yaniv
Burns, Laurie D.
Cocker, Eric D.
Hamel, Elizabeth O.
Ghosh, Kunal K.
Kitch, Lacey J.
El Gamal, Abbas
Schnitzer, Mark J.
author_facet Ziv, Yaniv
Burns, Laurie D.
Cocker, Eric D.
Hamel, Elizabeth O.
Ghosh, Kunal K.
Kitch, Lacey J.
El Gamal, Abbas
Schnitzer, Mark J.
author_sort Ziv, Yaniv
collection PubMed
description Via Ca(2+)-imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, for each day the ensemble representation of this environment involved a unique subset of cells. Yet, cells within the ∼15–25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks.
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spelling pubmed-37843082013-09-26 Long-term dynamics of CA1 hippocampal place codes Ziv, Yaniv Burns, Laurie D. Cocker, Eric D. Hamel, Elizabeth O. Ghosh, Kunal K. Kitch, Lacey J. El Gamal, Abbas Schnitzer, Mark J. Nat Neurosci Article Via Ca(2+)-imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, for each day the ensemble representation of this environment involved a unique subset of cells. Yet, cells within the ∼15–25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks. 2013-02-10 2013-03 /pmc/articles/PMC3784308/ /pubmed/23396101 http://dx.doi.org/10.1038/nn.3329 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Ziv, Yaniv
Burns, Laurie D.
Cocker, Eric D.
Hamel, Elizabeth O.
Ghosh, Kunal K.
Kitch, Lacey J.
El Gamal, Abbas
Schnitzer, Mark J.
Long-term dynamics of CA1 hippocampal place codes
title Long-term dynamics of CA1 hippocampal place codes
title_full Long-term dynamics of CA1 hippocampal place codes
title_fullStr Long-term dynamics of CA1 hippocampal place codes
title_full_unstemmed Long-term dynamics of CA1 hippocampal place codes
title_short Long-term dynamics of CA1 hippocampal place codes
title_sort long-term dynamics of ca1 hippocampal place codes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784308/
https://www.ncbi.nlm.nih.gov/pubmed/23396101
http://dx.doi.org/10.1038/nn.3329
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