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Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones

Protein kinase C (PKC) can dramatically alter cell structure and motility via effects on actin filament networks. In neurons, PKC activation has been implicated in repulsive guidance responses and inhibition of axon regeneration; however, the cytoskeletal mechanisms underlying these effects are not...

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Detalles Bibliográficos
Autores principales: Yang, Qing, Zhang, Xiao-Feng, Van Goor, David, Dunn, Ashleigh P., Hyland, Callen, Medeiros, Nelson, Forscher, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784383/
https://www.ncbi.nlm.nih.gov/pubmed/23966465
http://dx.doi.org/10.1091/mbc.E13-05-0289