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Microtubule Actin Cross-Linking Factor 1 Regulates Cardiomyocyte Microtubule Distribution and Adaptation to Hemodynamic Overload
Aberrant cardiomyocyte microtubule growth is a feature of pressure overload induced cardiac hypertrophy believed to contribute to left ventricular (LV) dysfunction. Microtubule Actin Cross-linking Factor 1 (MACF1/Acf7) is a 600 kd spectraplakin that stabilizes and guides microtubule growth along act...
Autores principales: | Fassett, John T., Xu, Xin, Kwak, Dongmin, Wang, Huan, Liu, Xiaoyu, Hu, Xinli, Bache, Robert J., Chen, Yingjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784444/ https://www.ncbi.nlm.nih.gov/pubmed/24086300 http://dx.doi.org/10.1371/journal.pone.0073887 |
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