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Polycation-π Interactions Are a Driving Force for Molecular Recognition by an Intrinsically Disordered Oncoprotein Family

Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions. However, some IDPs remain disordered in the bound state, a phenomenon coined “fuzziness”, often characterized by IDP polyvalency, sequence...

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Detalles Bibliográficos
Autores principales: Song, Jianhui, Ng, Sheung Chun, Tompa, Peter, Lee, Kevin A. W., Chan, Hue Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784488/
https://www.ncbi.nlm.nih.gov/pubmed/24086122
http://dx.doi.org/10.1371/journal.pcbi.1003239

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