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Polycation-π Interactions Are a Driving Force for Molecular Recognition by an Intrinsically Disordered Oncoprotein Family
Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions. However, some IDPs remain disordered in the bound state, a phenomenon coined “fuzziness”, often characterized by IDP polyvalency, sequence...
Autores principales: | Song, Jianhui, Ng, Sheung Chun, Tompa, Peter, Lee, Kevin A. W., Chan, Hue Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784488/ https://www.ncbi.nlm.nih.gov/pubmed/24086122 http://dx.doi.org/10.1371/journal.pcbi.1003239 |
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