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Histone Chaperone NAP1 Mediates Sister Chromatid Resolution by Counteracting Protein Phosphatase 2A
Chromosome duplication and transmission into daughter cells requires the precisely orchestrated binding and release of cohesin. We found that the Drosophila histone chaperone NAP1 is required for cohesin release and sister chromatid resolution during mitosis. Genome-wide surveys revealed that NAP1 a...
Autores principales: | Moshkin, Yuri M., Doyen, Cecile M., Kan, Tsung-Wai, Chalkley, Gillian E., Sap, Karen, Bezstarosti, Karel, Demmers, Jeroen A., Ozgur, Zeliha, van Ijcken, Wilfred F. J., Verrijzer, C. Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784504/ https://www.ncbi.nlm.nih.gov/pubmed/24086141 http://dx.doi.org/10.1371/journal.pgen.1003719 |
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