Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

Neutralizing and non-neutralizing antibodies to linear epitopes on HIV-1 envelope glycoproteins have potential to mediate antiviral effector functions that could be beneficial to vaccine-induced protection. Here, plasma IgG responses were assessed in three HIV-1 gp120 vaccine efficacy trials (RV144,...

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Detalles Bibliográficos
Autores principales: Gottardo, Raphael, Bailer, Robert T., Korber, Bette T., Gnanakaran, S., Phillips, Joshua, Shen, Xiaoying, Tomaras, Georgia D., Turk, Ellen, Imholte, Gregory, Eckler, Larry, Wenschuh, Holger, Zerweck, Johannes, Greene, Kelli, Gao, Hongmei, Berman, Phillip W., Francis, Donald, Sinangil, Faruk, Lee, Carter, Nitayaphan, Sorachai, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Tartaglia, James, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Zolla-Pazner, Susan, Haynes, Barton F., Mascola, John R., Self, Steve, Gilbert, Peter, Montefiori, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784573/
https://www.ncbi.nlm.nih.gov/pubmed/24086607
http://dx.doi.org/10.1371/journal.pone.0075665

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