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Alterations in mitochondrial DNA copy number and the activities of electron transport chain complexes and pyruvate dehydrogenase in the frontal cortex from subjects with autism
Autism is a neurodevelopmental disorder associated with social deficits and behavioral abnormalities. Recent evidence suggests that mitochondrial dysfunction and oxidative stress may contribute to the etiology of autism. This is the first study to compare the activities of mitochondrial electron tra...
Autores principales: | Gu, F, Chauhan, V, Kaur, K, Brown, W T, LaFauci, G, Wegiel, J, Chauhan, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784762/ https://www.ncbi.nlm.nih.gov/pubmed/24002085 http://dx.doi.org/10.1038/tp.2013.68 |
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