Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment

Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy. Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers). This brief review will discuss the...

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Detalles Bibliográficos
Autores principales: Gupta, Anu, Gupta, Yashdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784879/
https://www.ncbi.nlm.nih.gov/pubmed/24083177
http://dx.doi.org/10.4103/2230-8210.117215
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author Gupta, Anu
Gupta, Yashdeep
author_facet Gupta, Anu
Gupta, Yashdeep
author_sort Gupta, Anu
collection PubMed
description Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy. Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers). This brief review will discuss the pathophysiology behind glucocorticoid-induced myopathy, along with diagnostic features and treatment.
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spelling pubmed-37848792013-09-30 Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment Gupta, Anu Gupta, Yashdeep Indian J Endocrinol Metab Brief Communication Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy. Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers). This brief review will discuss the pathophysiology behind glucocorticoid-induced myopathy, along with diagnostic features and treatment. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3784879/ /pubmed/24083177 http://dx.doi.org/10.4103/2230-8210.117215 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Gupta, Anu
Gupta, Yashdeep
Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title_full Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title_fullStr Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title_full_unstemmed Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title_short Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
title_sort glucocorticoid-induced myopathy: pathophysiology, diagnosis, and treatment
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784879/
https://www.ncbi.nlm.nih.gov/pubmed/24083177
http://dx.doi.org/10.4103/2230-8210.117215
work_keys_str_mv AT guptaanu glucocorticoidinducedmyopathypathophysiologydiagnosisandtreatment
AT guptayashdeep glucocorticoidinducedmyopathypathophysiologydiagnosisandtreatment

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