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Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam

Because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. Fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (ATs). In this study, the effect of maternal AT...

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Autores principales: Atarod, Maryam, Shokrani, Parvaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785068/
https://www.ncbi.nlm.nih.gov/pubmed/24083135
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author Atarod, Maryam
Shokrani, Parvaneh
author_facet Atarod, Maryam
Shokrani, Parvaneh
author_sort Atarod, Maryam
collection PubMed
description Because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. Fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (ATs). In this study, the effect of maternal AT and depth in fetal dosimetry was investigated, using peripheral dose (PD) distribution evaluations. A BEAMnrc model of Oncor linac using out of beam components was used for dose calculations in out of field border. A 6 MV photon beam was used to irradiate a chest phantom. Measurements were done using EBT2 radiochromic film in a RW3 phantom as abdomen. The followings were measured for different ATs: Depth PD profiles at two distances from the field's edge, and in-plane PD profiles at two depths. The results of this study show that PD is depth dependent near the field's edge. The increase in AT does not change PD depth of maximum and its distribution as a function of distance from the field's edge. It is concluded that estimating the maximum fetal dose, using a flat phantom, i.e., without taking into account the AT, is possible. Furthermore, an in-plane profile measured at any depth can represent the dose variation as a function of distance. However, in order to estimate the maximum PD the depth of D(max) in out of field should be used for in-plane profile measurement.
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spelling pubmed-37850682013-09-30 Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam Atarod, Maryam Shokrani, Parvaneh J Med Signals Sens Original Article Because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. Fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (ATs). In this study, the effect of maternal AT and depth in fetal dosimetry was investigated, using peripheral dose (PD) distribution evaluations. A BEAMnrc model of Oncor linac using out of beam components was used for dose calculations in out of field border. A 6 MV photon beam was used to irradiate a chest phantom. Measurements were done using EBT2 radiochromic film in a RW3 phantom as abdomen. The followings were measured for different ATs: Depth PD profiles at two distances from the field's edge, and in-plane PD profiles at two depths. The results of this study show that PD is depth dependent near the field's edge. The increase in AT does not change PD depth of maximum and its distribution as a function of distance from the field's edge. It is concluded that estimating the maximum fetal dose, using a flat phantom, i.e., without taking into account the AT, is possible. Furthermore, an in-plane profile measured at any depth can represent the dose variation as a function of distance. However, in order to estimate the maximum PD the depth of D(max) in out of field should be used for in-plane profile measurement. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3785068/ /pubmed/24083135 Text en Copyright: © Journal of Medical Signals and Sensors http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Atarod, Maryam
Shokrani, Parvaneh
Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title_full Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title_fullStr Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title_full_unstemmed Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title_short Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam
title_sort monte carlo study of fetal dosimetry parameters for 6 mv photon beam
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785068/
https://www.ncbi.nlm.nih.gov/pubmed/24083135
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