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Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment

It has been suggested that the concentrations of tamoxifen and its demethylated metabolites increase with age. We measured the serum concentrations of the active tamoxifen metabolites, 4OHtamoxifen (4OHtam), 4-hydroxy-N-desmethyltamoxifen (4OHNDtam, Endoxifen), tamoxifen and its demethylated metabol...

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Detalles Bibliográficos
Autores principales:	Lien, Ernst A., Søiland, Håvard, Lundgren, Steinar, Aas, Turid, Steen, Vidar M., Mellgren, Gunnar, Gjerde, Jennifer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	Clinical Trial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785179/ https://www.ncbi.nlm.nih.gov/pubmed/23996142 http://dx.doi.org/10.1007/s10549-013-2677-9

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