A Case of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome with High ASLO Titer

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare autoimmune disease and the pathogenesis is still unknown. We report a case of TINU syndrome with high ASLO titer. Uveitis improved and urine β(2)-MG normalized with low dose systemic predonisolone and cyclosporin A. The high ASLO tit...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Yasuyo, Suzuki, Shunsuke, Fujioka, Tao, Oana, Shingo, Kawashima, Hisashi, Takekuma, Kouji, Hoshika, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785316/
https://www.ncbi.nlm.nih.gov/pubmed/24179369
Descripción
Sumario:Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare autoimmune disease and the pathogenesis is still unknown. We report a case of TINU syndrome with high ASLO titer. Uveitis improved and urine β(2)-MG normalized with low dose systemic predonisolone and cyclosporin A. The high ASLO titer in early phase suggested that streptococcal infection might have triggered TINU syndrome. Lymphocyte phenotypes normalized after treatment with low dose systemic predonisolone and cyclosporin A.

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