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A Strategy for Synthesis of Pathogenic Human Immunoglobulin Free Light Chains in E. coli

Monoclonal immunoglobulin light chains are normally synthesized in excess compared to the heavy chain partners and can be detected in serum and urine (“free” LC). Occasionally free LC are per se cause of organ toxicity, as in free LC-related disorders. In AL amyloidosis, the most common of these con...

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Detalles Bibliográficos
Autores principales:	Rognoni, Paola, Lavatelli, Francesca, Casarini, Simona, Palladini, Giovanni, Verga, Laura, Pedrazzoli, Paolo, Valentini, Giovanna, Merlini, Giampaolo, Perfetti, Vittorio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785434/ https://www.ncbi.nlm.nih.gov/pubmed/24086679 http://dx.doi.org/10.1371/journal.pone.0076022

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