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Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey

OBJECTIVE: To investigate the association between fasting plasma glucose level and pulmonary function. RESEARCH DESIGN AND METHODS: Nutritional information, pulmonary function data, and laboratory test data from 9,223 subjects from the fourth Korea National Health and Nutrition Examination Survey we...

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Autores principales: Lee, Yun Jeong, Kim, Na Kyung, Yang, Ju Yean, Noh, Jung Hyun, Lee, Sung-Soon, Ko, Kyung Soo, Rhee, Byoung Doo, Kim, Dong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785444/
https://www.ncbi.nlm.nih.gov/pubmed/24086719
http://dx.doi.org/10.1371/journal.pone.0076244
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author Lee, Yun Jeong
Kim, Na Kyung
Yang, Ju Yean
Noh, Jung Hyun
Lee, Sung-Soon
Ko, Kyung Soo
Rhee, Byoung Doo
Kim, Dong-Jun
author_facet Lee, Yun Jeong
Kim, Na Kyung
Yang, Ju Yean
Noh, Jung Hyun
Lee, Sung-Soon
Ko, Kyung Soo
Rhee, Byoung Doo
Kim, Dong-Jun
author_sort Lee, Yun Jeong
collection PubMed
description OBJECTIVE: To investigate the association between fasting plasma glucose level and pulmonary function. RESEARCH DESIGN AND METHODS: Nutritional information, pulmonary function data, and laboratory test data from 9,223 subjects from the fourth Korea National Health and Nutrition Examination Survey were examined. The participants were divided into five groups according to fasting plasma glucose (FPG) level: normal fasting glucose (NFG)1, FPG <90 mg/dl; NFG2, FPG 90-99 mg/dl; impaired fasting glucose (IFG)1: FPG 100-109 mg/dl; IFG2, FPG 110-125 mg/dl; and diabetes, FPG ≥126 mg/dl and/or current anti-diabetes medications. RESULTS: After adjustment for several variables, the percentage of predicted forced vital capacity(FVC%) decreased with increasing fasting plasma glucose level in both sexes[men: (mean ± SEM) 92.0±0.3 in NFG1; 91.9±0.3 in NFG2; 92.0±0.4 in IFG1; 90.2±0.7 in IFG2; and 89.9±0.5 in diabetes, P = 0.004; women: 93.7±0.3 in NFG1; 93.7±0.3 in NFG2; 93.1±0.5 in IFG1; 91.1±0.9 in IFG2; and 90.7±0.6 in diabetes, P<0.001]. A logistic regression analysis found that IFG2 and diabetes were independently associated with the lowest quintile of predicted FVC% (IFG2: odds ratio [95%CI], 1.50 [1.18-1.89], P = 0.001; diabetes: 1.56 [1.30-1.88], P<0.001) using NFG1 as a control. CONCLUSIONS: The current data suggest that forced vital capacity may begin to decrease in the higher range of IFG.
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spelling pubmed-37854442013-10-01 Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey Lee, Yun Jeong Kim, Na Kyung Yang, Ju Yean Noh, Jung Hyun Lee, Sung-Soon Ko, Kyung Soo Rhee, Byoung Doo Kim, Dong-Jun PLoS One Research Article OBJECTIVE: To investigate the association between fasting plasma glucose level and pulmonary function. RESEARCH DESIGN AND METHODS: Nutritional information, pulmonary function data, and laboratory test data from 9,223 subjects from the fourth Korea National Health and Nutrition Examination Survey were examined. The participants were divided into five groups according to fasting plasma glucose (FPG) level: normal fasting glucose (NFG)1, FPG <90 mg/dl; NFG2, FPG 90-99 mg/dl; impaired fasting glucose (IFG)1: FPG 100-109 mg/dl; IFG2, FPG 110-125 mg/dl; and diabetes, FPG ≥126 mg/dl and/or current anti-diabetes medications. RESULTS: After adjustment for several variables, the percentage of predicted forced vital capacity(FVC%) decreased with increasing fasting plasma glucose level in both sexes[men: (mean ± SEM) 92.0±0.3 in NFG1; 91.9±0.3 in NFG2; 92.0±0.4 in IFG1; 90.2±0.7 in IFG2; and 89.9±0.5 in diabetes, P = 0.004; women: 93.7±0.3 in NFG1; 93.7±0.3 in NFG2; 93.1±0.5 in IFG1; 91.1±0.9 in IFG2; and 90.7±0.6 in diabetes, P<0.001]. A logistic regression analysis found that IFG2 and diabetes were independently associated with the lowest quintile of predicted FVC% (IFG2: odds ratio [95%CI], 1.50 [1.18-1.89], P = 0.001; diabetes: 1.56 [1.30-1.88], P<0.001) using NFG1 as a control. CONCLUSIONS: The current data suggest that forced vital capacity may begin to decrease in the higher range of IFG. Public Library of Science 2013-09-27 /pmc/articles/PMC3785444/ /pubmed/24086719 http://dx.doi.org/10.1371/journal.pone.0076244 Text en © 2013 Lee et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Lee, Yun Jeong
Kim, Na Kyung
Yang, Ju Yean
Noh, Jung Hyun
Lee, Sung-Soon
Ko, Kyung Soo
Rhee, Byoung Doo
Kim, Dong-Jun
Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title_full Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title_fullStr Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title_full_unstemmed Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title_short Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
title_sort low pulmonary function in individuals with impaired fasting glucose: the 2007-2009 korea national health and nutrition examination survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785444/
https://www.ncbi.nlm.nih.gov/pubmed/24086719
http://dx.doi.org/10.1371/journal.pone.0076244
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