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Low Molecular Weight Protein Tyrosine Phosphatase Isoforms Regulate Breast Cancer Cells Migration through a RhoA Dependent Mechanism

Low molecular weight protein tyrosine phosphatase (LMW-PTP) has been associated with cell proliferation control through dephosphorylation and inactivation of growth factor receptors such as PDGF-R and EphA2, and with cellular adhesion and migration through p190RhoGap and RhoA. We aim to clarify the...

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Detalles Bibliográficos
Autores principales: Alho, Irina, Costa, Luis, Bicho, Manuel, Coelho, Constança
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785452/
https://www.ncbi.nlm.nih.gov/pubmed/24086724
http://dx.doi.org/10.1371/journal.pone.0076307