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Molecular Dynamics Study of Zn(Aβ) and Zn(Aβ)(2)
The aggregation of Aβ-peptide (Aβ) is widely considered to be the critical step in the pathology of Alzheimer's disease. Small, soluble Aβ oligomers have been shown to be more neurotoxic than large, insoluble aggregates and fibrils. Recent studies suggest that biometal ions, including Zn(II), m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785486/ https://www.ncbi.nlm.nih.gov/pubmed/24086248 http://dx.doi.org/10.1371/journal.pone.0070681 |