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Commensal Microbiota Contributes to Chronic Endocarditis in TAX1BP1 Deficient Mice
Tax1-binding protein 1 (Tax1bp1) negatively regulates NF-κB by editing the ubiquitylation of target molecules by its catalytic partner A20. Genetically engineered TAX1BP1-deficient (KO) mice develop age-dependent inflammatory constitutions in multiple organs manifested as valvulitis or dermatitis an...
Autores principales: | Nakano, Satoko, Ikebe, Emi, Tsukamoto, Yoshiyuki, Wang, Yan, Matsumoto, Takashi, Mitsui, Takahiro, Yahiro, Takaaki, Inoue, Kunimitsu, Kawazato, Hiroaki, Yasuda, Aiko, Ito, Kanako, Yokoyama, Shigeo, Takahashi, Naohiko, Hori, Mitsuo, Shimada, Tatsuo, Moriyama, Masatsugu, Kubota, Toshiaki, Ono, Katsushige, Fujibuchi, Wataru, Jeang, Kuan-Teh, Iha, Hidekatsu, Nishizono, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785488/ https://www.ncbi.nlm.nih.gov/pubmed/24086273 http://dx.doi.org/10.1371/journal.pone.0073205 |
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