Cargando…

Streptochlorin Suppresses Allergic Dermatitis and Mast Cell Activation via Regulation of Lyn/Fyn and Syk Signaling Pathways in Cellular and Mouse Models

Allergic diseases are chronic inflammatory conditions with specific immune and inflammatory mechanisms. Scientific interest in understanding the mechanisms and discovering novel agents for the prevention and treatment of allergic disease is increasing. Streptochlorin, a small compound derived from m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Seung-Hwan, Shin, Hee Jae, Kim, Dong-Young, Shim, Do-Wan, Kim, Tack-Joong, Ye, Sang-Kyu, Won, Hyung-Sik, Koppula, Sushruta, Kang, Tae-Bong, Lee, Kwang-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785495/ https://www.ncbi.nlm.nih.gov/pubmed/24086321 http://dx.doi.org/10.1371/journal.pone.0074194

Ejemplares similares

Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice
por: Lee, Dajeong, et al.
Publicado: (2020)

Anti-Inflammatory Effect of Streptochlorin via TRIF-Dependent Signaling Pathways in Cellular and Mouse Models
por: Shim, Do-Wan, et al.
Publicado: (2015)

Ethanol Extract of Sesamum indicum Linn. Inhibits FcεRI-Mediated Allergic Reaction via Regulation of Lyn/Syk and Fyn Signaling Pathways in Rat Basophilic Leukemic RBL-2H3 Mast Cells
por: Do, Hyun Ju, et al.
Publicado: (2019)

Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels
por: Dhakal, Hima, et al.
Publicado: (2019)

Rhamnus davurica leaf extract inhibits Fyn activation by antigen in mast cells for anti-allergic activity
por: Kim, Ji Hyung, et al.
Publicado: (2015)

Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma
por: Kwak, Tae Won, et al.
Publicado: (2015)

Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation
por: Mkaddem, Sanae Ben, et al.
Publicado: (2017)

Suppressive Effects of Vaccinium angustifolium Root Extract via Down-Regulation of Activation of Syk, Lyn, and NF-κB in FcɛRI-Mediated Allergic Reactions
por: Shim, Sun-Yup
Publicado: (2018)

Neuroblastoma Tyrosine Kinase Signaling Networks Involve FYN and LYN in Endosomes and Lipid Rafts
por: Palacios-Moreno, Juan, et al.
Publicado: (2015)

Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
Publicado: (1996)

Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
por: Tiemi Shio, Marina, et al.
Publicado: (2009)

Luxeptinib interferes with LYN-mediated activation of SYK and modulates BCR signaling in lymphoma
por: Sonowal, Himangshu, et al.
Publicado: (2023)

Tricin Isolated from Enzyme-Treated Zizania latifolia Extract Inhibits IgE-Mediated Allergic Reactions in RBL-2H3 Cells by Targeting the Lyn/Syk Pathway
por: Lee, Jae-Yeul, et al.
Publicado: (2020)

Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
por: Dallari, S., et al.
Publicado: (2017)

Correction: Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
por: Shio, Marina Tiemi, et al.
Publicado: (2009)

Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1
por: Kanagy, William K., et al.
Publicado: (2022)

Discovery of Novel Pimprinine and Streptochlorin Derivatives as Potential Antifungal Agents
por: Liu, Jing-Rui, et al.
Publicado: (2022)

Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction
por: Qian, Fei, et al.
Publicado: (2019)

Caffeoyl-Prolyl-Histidine Amide Inhibits Fyn and Alleviates Atopic Dermatitis-Like Phenotypes via Suppression of NF-κB Activation
por: Jeong, Hayan, et al.
Publicado: (2020)

An Anti-Cancer Drug Candidate CYC116 Suppresses Type I Hypersensitive Immune Responses through the Inhibition of Fyn Kinase in Mast Cells
por: Park, Young Hwan, et al.
Publicado: (2019)

Potential Natural Biomolecules Targeting JAK/STAT/SOCS Signaling in the Management of Atopic Dermatitis
por: Kopalli, Spandana Rajendra, et al.
Publicado: (2022)

BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination
por: Shim, Do-Wan, et al.
Publicado: (2017)

Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype
por: Nunes de Miranda, Susana M., et al.
Publicado: (2016)

Design, Synthesis, Antifungal Activity, and Molecular Docking of Streptochlorin Derivatives Containing the Nitrile Group
por: Liu, Jing-Rui, et al.
Publicado: (2023)

Coupling Ca(2+) store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases
por: Chung, S. Clare, et al.
Publicado: (2007)

CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein
Publicado: (1994)

AT9283, 1-Cyclopropyl-3-(3-(5-(Morpholinomethyl)-1H-Benzo[d] Imidazole-2-yl)-1H-Pyrazol-4-yl) Urea, Inhibits Syk to Suppress Mast Cell-Mediated Allergic Response
por: Kim, Su Jeong, et al.
Publicado: (2022)

A Case of Autoimmune Progesterone Dermatitis Misdiagnosed as Allergic Contact Dermatitis
por: Lee, Myoung Kyu, et al.
Publicado: (2011)

Negative Regulation of Immunoglobulin E–dependent Allergic Responses by Lyn Kinase
por: Odom, Sandra, et al.
Publicado: (2004)

Britanin Suppresses IgE/Ag-Induced Mast Cell Activation by Inhibiting the Syk Pathway
por: Lu, Yue, et al.
Publicado: (2014)

Identification and Characterization of NTB451 as a Potential Inhibitor of Necroptosis
por: In, Eun-Jung, et al.
Publicado: (2018)

Regulation and Function of Syk Tyrosine Kinase in Mast Cell Signaling and Beyond
por: de Castro, Rodrigo Orlandini
Publicado: (2011)

Physical and Functional Association of the Src Family Kinases Fyn and Lyn with the Collagen Receptor Glycoprotein VI-Fc Receptor γ Chain Complex on Human Platelets
por: Ezumi, Yasuharu, et al.
Publicado: (1998)

Evaluating the Nickel Content in Metal Alloys and the Threshold for Nickel-Induced Allergic Contact Dermatitis
por: Kim, Yoon Young, et al.
Publicado: (2008)

Inhibitory Effect and Mechanism of Arctium lappa Extract on NLRP3 Inflammasome Activation
por: Kim, Young-Kyu, et al.
Publicado: (2018)

Allergic Contact Dermatitis Caused by Topical Eye Drops Containing Latanoprost
por: Lee, Ji Hye, et al.
Publicado: (2014)

The Fine Scratches of the Spectacle Frames and the Allergic Contact Dermatitis
por: Kim, In Su, et al.
Publicado: (2013)

Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation
por: Kwak, Su-Bin, et al.
Publicado: (2018)

Effects of Cymbidium Root Ethanol Extract on Atopic Dermatitis
por: Kim, Wan-Joong, et al.
Publicado: (2016)

Allergic contact dermatitis caused by dorzolamide eyedrops
por: Lee, Seung-Jun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8b81oi49f3lomtkgvpt5pik9mj