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Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer

Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences are poorly understood. We report an analysis of β-dystroglycan in prostate cancer in human tissue samples and in LNCaP cells in vitro. There is progressive loss of β-dystroglycan immunoreactivity from basal and la...

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Detalles Bibliográficos
Autores principales:	Mathew, G., Mitchell, A., Down, J. M., Jacobs, L. A., Hamdy, F. C., Eaton, C., Rosario, D. J., Cross, S. S., Winder, S. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786294/ https://www.ncbi.nlm.nih.gov/pubmed/24077328 http://dx.doi.org/10.1038/srep02792

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