Multiple genetic origins of histidine-rich protein 2 gene deletion in Plasmodium falciparum parasites from Peru

The majority of malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2), encoded by the pfhrp2 gene. Recently, P. falciparum isolates from Peru were found to lack pfhrp2 leading to false-negative RDT results. We hypothesized that pfhrp2-deleted parasites...

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Detalles Bibliográficos
Autores principales: Akinyi, Sheila, Hayden, Tonya, Gamboa, Dionicia, Torres, Katherine, Bendezu, Jorge, Abdallah, Joseph F., Griffing, Sean M., Quezada, Wilmer Marquiño, Arrospide, Nancy, De Oliveira, Alexandre Macedo, Lucas, Carmen, Magill, Alan J., Bacon, David J., Barnwell, John W., Udhayakumar, Venkatachalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786299/
https://www.ncbi.nlm.nih.gov/pubmed/24077522
http://dx.doi.org/10.1038/srep02797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786299/
https://www.ncbi.nlm.nih.gov/pubmed/24077522
http://dx.doi.org/10.1038/srep02797

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