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Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats

Cataracts are a major cause of human blindness. Aldose reductase (AR) is an important rate-limiting enzyme that contributes to cataract induction in diabetic patients. Scopoletin is the main bioactive constituent of flower buds from Magnolia fargesii and is known to inhibit AR activity. To assess sc...

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Detalles Bibliográficos
Autores principales: Kim, Junghyun, Kim, Chan-Sik, Lee, Yun Mi, Sohn, Eunjin, Jo, Kyuhyung, Shin, So Dam, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786474/
https://www.ncbi.nlm.nih.gov/pubmed/24101940
http://dx.doi.org/10.1155/2013/787138