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Aberrant Alternative Splicing Is Another Hallmark of Cancer
The vast majority of human genes are alternatively spliced. Not surprisingly, aberrant alternative splicing is increasingly linked to cancer. Splice isoforms often encode proteins that have distinct and even antagonistic properties. The abnormal expression of splice factors and splice factor kinases...
Autor principal: | Ladomery, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786539/ https://www.ncbi.nlm.nih.gov/pubmed/24101931 http://dx.doi.org/10.1155/2013/463786 |
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