Cargando…

Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction

The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the b...

Descripción completa

Detalles Bibliográficos
Autores principales: Cottone, Erika, Pomatto, Valentina, Bovolin, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786540/
https://www.ncbi.nlm.nih.gov/pubmed/24101926
http://dx.doi.org/10.1155/2013/941237
_version_ 1782477756903194624
author Cottone, Erika
Pomatto, Valentina
Bovolin, Patrizia
author_facet Cottone, Erika
Pomatto, Valentina
Bovolin, Patrizia
author_sort Cottone, Erika
collection PubMed
description The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins.
format Online
Article
Text
id pubmed-3786540
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37865402013-10-07 Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction Cottone, Erika Pomatto, Valentina Bovolin, Patrizia Int J Endocrinol Review Article The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins. Hindawi Publishing Corporation 2013 2013-09-11 /pmc/articles/PMC3786540/ /pubmed/24101926 http://dx.doi.org/10.1155/2013/941237 Text en Copyright © 2013 Erika Cottone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Cottone, Erika
Pomatto, Valentina
Bovolin, Patrizia
Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_full Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_fullStr Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_full_unstemmed Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_short Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_sort role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786540/
https://www.ncbi.nlm.nih.gov/pubmed/24101926
http://dx.doi.org/10.1155/2013/941237
work_keys_str_mv AT cottoneerika roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction
AT pomattovalentina roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction
AT bovolinpatrizia roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction