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Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786540/ https://www.ncbi.nlm.nih.gov/pubmed/24101926 http://dx.doi.org/10.1155/2013/941237 |
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author | Cottone, Erika Pomatto, Valentina Bovolin, Patrizia |
author_facet | Cottone, Erika Pomatto, Valentina Bovolin, Patrizia |
author_sort | Cottone, Erika |
collection | PubMed |
description | The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins. |
format | Online Article Text |
id | pubmed-3786540 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37865402013-10-07 Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction Cottone, Erika Pomatto, Valentina Bovolin, Patrizia Int J Endocrinol Review Article The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins. Hindawi Publishing Corporation 2013 2013-09-11 /pmc/articles/PMC3786540/ /pubmed/24101926 http://dx.doi.org/10.1155/2013/941237 Text en Copyright © 2013 Erika Cottone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cottone, Erika Pomatto, Valentina Bovolin, Patrizia Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_full | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_fullStr | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_full_unstemmed | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_short | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_sort | role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786540/ https://www.ncbi.nlm.nih.gov/pubmed/24101926 http://dx.doi.org/10.1155/2013/941237 |
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