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Daily physical activity in subjects with newly diagnosed COPD

RATIONALE: Information about daily physical activity levels (PAL) in subjects with undiagnosed chronic obstructive pulmonary disease (COPD) is scarce. This study aims to assess PA and to investigate the associations between PA and clinical characteristics in subjects with newly diagnosed COPD. METHO...

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Autores principales: Van Remoortel, Hans, Hornikx, Miek, Demeyer, Heleen, Langer, Daniel, Burtin, Chris, Decramer, Marc, Gosselink, Rik, Janssens, Wim, Troosters, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786635/
https://www.ncbi.nlm.nih.gov/pubmed/23604460
http://dx.doi.org/10.1136/thoraxjnl-2013-203534
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author Van Remoortel, Hans
Hornikx, Miek
Demeyer, Heleen
Langer, Daniel
Burtin, Chris
Decramer, Marc
Gosselink, Rik
Janssens, Wim
Troosters, Thierry
author_facet Van Remoortel, Hans
Hornikx, Miek
Demeyer, Heleen
Langer, Daniel
Burtin, Chris
Decramer, Marc
Gosselink, Rik
Janssens, Wim
Troosters, Thierry
author_sort Van Remoortel, Hans
collection PubMed
description RATIONALE: Information about daily physical activity levels (PAL) in subjects with undiagnosed chronic obstructive pulmonary disease (COPD) is scarce. This study aims to assess PA and to investigate the associations between PA and clinical characteristics in subjects with newly diagnosed COPD. METHODS: Fifty-nine subjects with a new spirometry-based diagnosis of mild (n=38) and moderate (n=21) COPD (63±6 years, 68% male) were matched with 65 smoking controls (62±7 years, 75% male). PA (daily steps, time spent in moderate-to-vigorous intense physical activities (MVPA) and PAL) was measured by accelerometry. Dyspnoea, complete pulmonary function tests, peripheral muscle strength and exercise capacity served as clinical characteristics. RESULTS: PA was significantly lower in COPD versus smoking controls (7986±2648 vs 9765±3078 steps, 64 (27–120) vs 110 (55–164) min of MVPA, 1.49±0.21 vs 1.62±0.24 PAL respectively, all p<0.05). Subjects with COPD with either mild symptoms of dyspnoea (mMRC 1), those with lower diffusion capacity (T(L),co), low 6 min walking distance (6MWD) or low maximal oxygen uptake (VO(2) peak) had significantly lower PA. Multiple regression analysis identified 6 MWD and T(L),co as independent predictors of PA in COPD. CONCLUSIONS: The reduction in PA starts early in the disease, even when subjects are not yet diagnosed with COPD. Inactivity is more pronounced in subjects with mild symptoms of dyspnoea, lower levels of diffusion capacity and exercise capacity.
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spelling pubmed-37866352013-09-30 Daily physical activity in subjects with newly diagnosed COPD Van Remoortel, Hans Hornikx, Miek Demeyer, Heleen Langer, Daniel Burtin, Chris Decramer, Marc Gosselink, Rik Janssens, Wim Troosters, Thierry Thorax Research Letter RATIONALE: Information about daily physical activity levels (PAL) in subjects with undiagnosed chronic obstructive pulmonary disease (COPD) is scarce. This study aims to assess PA and to investigate the associations between PA and clinical characteristics in subjects with newly diagnosed COPD. METHODS: Fifty-nine subjects with a new spirometry-based diagnosis of mild (n=38) and moderate (n=21) COPD (63±6 years, 68% male) were matched with 65 smoking controls (62±7 years, 75% male). PA (daily steps, time spent in moderate-to-vigorous intense physical activities (MVPA) and PAL) was measured by accelerometry. Dyspnoea, complete pulmonary function tests, peripheral muscle strength and exercise capacity served as clinical characteristics. RESULTS: PA was significantly lower in COPD versus smoking controls (7986±2648 vs 9765±3078 steps, 64 (27–120) vs 110 (55–164) min of MVPA, 1.49±0.21 vs 1.62±0.24 PAL respectively, all p<0.05). Subjects with COPD with either mild symptoms of dyspnoea (mMRC 1), those with lower diffusion capacity (T(L),co), low 6 min walking distance (6MWD) or low maximal oxygen uptake (VO(2) peak) had significantly lower PA. Multiple regression analysis identified 6 MWD and T(L),co as independent predictors of PA in COPD. CONCLUSIONS: The reduction in PA starts early in the disease, even when subjects are not yet diagnosed with COPD. Inactivity is more pronounced in subjects with mild symptoms of dyspnoea, lower levels of diffusion capacity and exercise capacity. BMJ Publishing Group 2013-10 2013-04-20 /pmc/articles/PMC3786635/ /pubmed/23604460 http://dx.doi.org/10.1136/thoraxjnl-2013-203534 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Research Letter
Van Remoortel, Hans
Hornikx, Miek
Demeyer, Heleen
Langer, Daniel
Burtin, Chris
Decramer, Marc
Gosselink, Rik
Janssens, Wim
Troosters, Thierry
Daily physical activity in subjects with newly diagnosed COPD
title Daily physical activity in subjects with newly diagnosed COPD
title_full Daily physical activity in subjects with newly diagnosed COPD
title_fullStr Daily physical activity in subjects with newly diagnosed COPD
title_full_unstemmed Daily physical activity in subjects with newly diagnosed COPD
title_short Daily physical activity in subjects with newly diagnosed COPD
title_sort daily physical activity in subjects with newly diagnosed copd
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786635/
https://www.ncbi.nlm.nih.gov/pubmed/23604460
http://dx.doi.org/10.1136/thoraxjnl-2013-203534
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