Cargando…

Environmental Impact on Direct Neuronal Reprogramming In Vivo in the Adult Brain

Direct reprogramming of non-neuronal cells to generate new neurons is a promising approach to repair damaged brains. Impact of the in vivo environment on neuronal reprogramming, however, is poorly understood. Here we show that regional differences and injury conditions have significant influence on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grande, Andrew, Sumiyoshi, Kyoko, López-Juárez, Alejandro, Howard, Jennifer, Sakthivel, Bhuvaneswari, Aronow, Bruce, Campbell, Kenneth, Nakafuku, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786770/ https://www.ncbi.nlm.nih.gov/pubmed/23974433 http://dx.doi.org/10.1038/ncomms3373

Ejemplares similares

In Vivo Reprogramming for Brain and Spinal Cord Repair
por: Chen, Gong, et al.
Publicado: (2015)

In vivo direct reprogramming of glial linage to mature neurons after cerebral ischemia
por: Yamashita, Toru, et al.
Publicado: (2019)

In vivo chemical reprogramming of astrocytes into neurons
por: Ma, Yantao, et al.
Publicado: (2021)

Direct neuronal reprogramming by temporal identity factors
por: Boudreau-Pinsonneault, Camille, et al.
Publicado: (2023)

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons
por: Luo, Chongyuan, et al.
Publicado: (2019)

Regeneration of the cerebral cortex by direct chemical reprogramming of macrophages into neuronal cells in acute ischemic stroke
por: Ninomiya, Itaru, et al.
Publicado: (2023)

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway
por: Nagao, Motoshi, et al.
Publicado: (2008)

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway
por: Nagao, Motoshi, et al.
Publicado: (2009)

Using transcription factors for direct reprogramming of neurons in vitro
por: El Wazan, Layal, et al.
Publicado: (2019)

The iNs and Outs of Direct Reprogramming to Induced Neurons
por: Carter, Jasmine L., et al.
Publicado: (2020)

Current Approaches and Molecular Mechanisms for Directly Reprogramming Fibroblasts Into Neurons and Dopamine Neurons
por: Han, Fabin, et al.
Publicado: (2021)

Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells
por: Liu, Xinjian, et al.
Publicado: (2012)

Direct reprogramming of human astrocytes into neural stem cells and neurons
por: Corti, Stefania, et al.
Publicado: (2012)

Transient CREB-mediated transcription is key in direct neuronal reprogramming
por: Gascón, Sergio, et al.
Publicado: (2017)

Direct neuronal reprogramming of olfactory ensheathing cells for CNS repair
por: Sun, Xiu, et al.
Publicado: (2019)

Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming
por: Cheng, Xueyan, et al.
Publicado: (2019)

Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors
por: Colasante, Gaia, et al.
Publicado: (2019)

Direct Reprogramming of Somatic Cells to Neurons: Pros and Cons of Chemical Approach
por: Mollinari, Cristiana, et al.
Publicado: (2021)

A quantitative model of cellular decision making in direct neuronal reprogramming
por: Merlevede, Adriaan, et al.
Publicado: (2021)

Application of Small Molecules in the Central Nervous System Direct Neuronal Reprogramming
por: Wang, Jingyi, et al.
Publicado: (2022)

Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
por: Tang, Yu, et al.
Publicado: (2017)

In vivo direct reprogramming as a therapeutic strategy for brain and retina repair
por: Sekiryu, Haruka, et al.
Publicado: (2021)

Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities
por: Felske, Torsten, et al.
Publicado: (2023)

Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders
por: Hou, Shaoping, et al.
Publicado: (2016)

Direct Neuronal Reprogramming: Bridging the Gap Between Basic Science and Clinical Application
por: Vasan, Lakshmy, et al.
Publicado: (2021)

Protocol Optimization for Direct Reprogramming of Primary Human Fibroblast into Induced Striatal Neurons
por: Kraskovskaya, Nina, et al.
Publicado: (2023)

Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming
por: Herrero-Navarro, Álvaro, et al.
Publicado: (2021)

Sonoporation-Mediated Gene Transfection: A Novel Direction for Cell Reprogramming In Vivo
por: Du, Meng, et al.
Publicado: (2022)

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo
por: He, Songwei, et al.
Publicado: (2015)

Targeting PTB for Glia-to-Neuron Reprogramming In Vitro and In Vivo for Therapeutic Development in Neurological Diseases
por: Contardo, Matilde, et al.
Publicado: (2022)

In vivo astrocyte-to-neuron reprogramming for central nervous system regeneration: a narrative review
por: Talifu, Zuliyaer, et al.
Publicado: (2022)

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?
por: Drouin-Ouellet, Janelle, et al.
Publicado: (2017)

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
por: Treutlein, Barbara, et al.
Publicado: (2016)

Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration
por: Habekost, Mette, et al.
Publicado: (2021)

Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide
por: Wong, Hector R, et al.
Publicado: (2008)

Direct Reprogramming of Resident Non-Myocyte Cells and Its Potential for In Vivo Cardiac Regeneration
por: Perveen, Sadia, et al.
Publicado: (2023)

Direct reprogramming of fibroblasts into cardiomyocytes
por: Chen, Yueqiu, et al.
Publicado: (2017)

Direct Reprogramming of Spiral Ganglion Non-neuronal Cells into Neurons: Toward Ameliorating Sensorineural Hearing Loss by Gene Therapy
por: Noda, Teppei, et al.
Publicado: (2018)

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry
por: Torper, Olof, et al.
Publicado: (2015)

Corrigendum: In vivo astrocyte-to-neuron reprogramming for central nervous system regeneration: a narrative review
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bbmi4q76rrps1e7g6d7pa5n00c